The vasodilatory neuropeptide, calcitonin gene-related peptide, may be instrumental in the genesis of hot flashes.

"There's a host of common neurotransmitters that are shared here," he says, including calcitonin gene-related peptide, histamines and cytokines.

Olcegepant is an calcitonin gene-related peptide receptor antagonists which is being studied regarding a potential effect in migraines.

Pregabalin decreases the release of neurotransmitters including glutamate, norepinephrine, substance P and calcitonin gene-related peptide.

The drug works by inhibiting a protein released during inflammation, called calcitonin gene-related peptide (CGRP).

The calcitonin gene-related peptide (CGRP) is a strong vasodilator primarily found in nervous tissue.

The nerve cells secrete a chemical known as calcitonin gene-related peptide, or CGRP, which is normally used to transmit messages between nerves.

Telcagepant acts as a calcitonin gene-related peptide receptor (CRLR) antagonist and blocks this peptide.

Coming soon: Telecagepant: This drug blocks the receptor of calcitonin gene-related peptide (CGRP), a substance that's released during migraines.

The presynaptic terminal bouton is filled with vesicles containing acetylcholine and a neuropeptide called Calcitonin gene-related peptide (CGRP).

Millet, I., et al., Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide.

Research has revealed that nitric oxide (NO) and calcitonin gene-related peptide (CGRP) do have roles in the pathogenesis of a migraine without aura attack.

In MTC, the flushing, diarrhea, and itching (pruritis) are all caused by elevated levels of calcitonin gene products (calcitonin or calcitonin gene-related peptide).

These include vasopressin, oxytocin, VIP, NPY, peptide histidine isoleucine, calcitonin gene-related peptide, substance P and somastotin.

The CALC1 gene belongs to a superfamily of related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin.

Alternative splicing of the gene coding for calcitonin produces a distantly related peptide of 37 amino acids, called calcitonin gene-related peptide (CGRP), beta type.

This action inhibits the release of pro-nociceptive neurochemicals like glutamate, calcitonin gene-related peptide (CGRP), and substance P in the brain and spinal cord, resulting in pain relief.

Neurogenic inflammation is inflammation arising from the local release from afferent neurons of inflammatory mediators such as Substance P and Calcitonin Gene-Related Peptide (CGRP).

Calcitonin gene-related peptide receptor antagonists are a class of medications that inhibit the calcitonin gene-related peptide (CGRP) receptor.

They can be distinguished by their profile of bioactive amines and peptides, namely serotonin, calcitonin, calcitonin gene-related peptide (CGRP), chromogranin A, gastrin-releasing peptide (GRP), and cholecystokinin.

The two signaling molecules released by the axon are calcitonin gene-related peptide (CGRP) and neuregulin, which trigger a series of kinases that eventually lead to transcriptional activation of the AChR genes.

CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed.

It is noteworthy that among the genes analyzed that were not found to be significantly regulated when tested in multiple monkeys 4 h after antigen challenge, there were two genes from cluster E: for fibronectin and calcitonin gene-related peptide receptor-1 (CGRP-R1).