Appel reaction

The Appel reaction begins with the formation of the phosphonium salt 2.

A novel variant of the Appel reaction has been noted for sulfenamides.

The Appel reaction is also useful for preparing alkyl halides.

Alcohols are converted in and to iodide, by a mechanism similar to the Appel reaction.

In an Appel reaction carbon tetrachloride is used to generate the chloride from alcohols.

This property is used in the Appel reaction for converting alcohols to alkyl halides.

In organic chemistry, carbon tetrachloride serves as a source of chlorine in the Appel reaction.

Finally, methods that do not form HCl are also known, such as the Appel reaction:

Alternatively, the Appel reaction:

Illustrative use of the Appel reaction is the chlorination of geraniol to geranyl chloride.

The Appel reaction is an organic reaction that converts an alcohol into an alkyl chloride using triphenylphosphine and carbon tetrachloride.

In combination with triphenylphosphine, CBr is used in the Appel reaction, which converts alcohols to alkyl bromides.

The alcohol group was replaced by bromine in an Appel reaction which caused an elimination reaction (loss of HBr) to cyclopropane 3.12.

He was a research assistant in Chemistry at Bonn University in Bonn, when he developed the Appel reaction.

In this variant reaction the triphenyl phosphine forms a double bonded linkage with nitrogen in the sulfenamide instead of oxygen as is customary in the Appel reaction.