Some services, such as Toronto EMS, continue to train advanced care paramedics internally.

Advanced Care Paramedic (ACP)

This will maintain a call-volume around 10,000 calls per year and will warrant the addition of Advanced Care Paramedic (ACP) resources to the station (e.g., Chilliwack).

John Murdoch Bignell (April 10, 1975 - Present) is a Nova Scotia Advanced Care Paramedic, Nova Scotia Funeral Director, and Halifax Business man.

Station 40 is an Advanced Life Support and Basic Life Support station staffed with Level II (Advanced Care Paramedic) and Level I (Primary Care Paramedic) crews located at 58 Richmond Street East.

Many Paramedics in Canada at all levels from Primary Care Paramedic, Advanced Care Paramedic and Critical Care Paramedic are combining their diploma of paramedicine with a bachelors degree of paramedicine which is heading towards the standard of educational requirements in Canada.

The mupirocin pathway also contains several tandem acyl carrier protein doublets or triplets.

The structures of a number of acyl carrier proteins have been solved using various NMR and crystallography techniques.

One of the biological ethers used in the synthesis of fats is a β- mercaptoethylamine-pantothenate complex associated with an acyl carrier protein.

The octanoate is transferred from a thioester of acyl carrier protein to an amide of the lipoyl domain by an octanoyltransferase.

Other names in common use include stearyl acyl carrier protein desaturase, and stearyl-ACP desaturase.

Octanoyl-(acyl carrier protein):protein N-octanoyltransferases, or octanoyltransferases, are required for lipoic acid biosynthesis.

Acyl carrier protein (ACP)

Subsequently elongation of an activated malonyl unit covalently attached to an acyl carrier protein by a ketosynthase occurs giving the five carbon unit.

When found in foods, most pantothenic acid is in the form of CoA or acyl carrier protein (ACP).

The DEBS complex also contains a Loading Domain on module 1 consisting of an acyl carrier protein and an acyltransferase.

The acyl groups are loaded onto the acyl carrier protein (ACP) with the help of the acyltransferase (AT) domain.

They transfer octanoate from the acyl carrier protein (ACP), part of fatty acid biosynthesis, to the specific lysine residue of lipoyl domains.

Every polyketide synthase module has an acyl carrier protein (ACP) and a ketosynthase domain that collaborate to catalyze the chain elongation.

Thus, the two substrates of this enzyme are malonyl-CoA and acyl carrier protein, whereas its two products are CoA and malonyl-acyl-carrier-protein.

Coenzyme A is also the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.

In both fatty acid synthesis and polyketide synthesis, the intermediates are covalently bound to ACP, or Acyl Carrier Protein.

Malonyl-CoA is utilised in fatty acid biosynthesis by the enzyme malonyl coenzyme A:acyl carrier protein transacylase (MCAT).

Abbreviations: ACP - Acyl carrier protein, CoA - Coenzyme A, NADP - Nicotinamide adenine dinucleotide phosphate.

PPT attaches the 4'-phosphopantetheine prosthetic group of CoA to the acyl carrier protein (ACP) domain, which is found in the N terminus of the α subunit.

After QC is biosynthesized, the adenylation domain-containing Ecm1 activates and transfers QC to FabC using the fatty acid biosynthesis acyl carrier protein (ACP).

Gcs exhibits high substrate flexibility accepting a variety of acyl groups carried and transferred through a thioester bond by either coenzyme A (CoA) or acyl carrier protein (ACP).

These thioesters are made by conjugating the fatty acid with the free SH group of the pantetheine moiety of either coenzyme A (CoA) or acyl carrier protein (ACP).

The enzyme MCAT together with an acyl carrier protein (ACP), and a polyketide synthase and chain-length factor heterodimer, constitutes the minimal PKS of type II polyketides.

The starting unit is then modified by a series of Claisen condensations with malonyl or methylmalonyl substrates, which are attached to an acyl carrier protein (ACP) and extend the polyketide by two carbons each.

Other enzymes in this pathway have similarly been proven antibiotic targets for example FabI, the enoyl-ACP (acyl carrier protein) reductase, that is inhibited by isoniazid and related compounds and the antiseptic agent triclosan.