"mutation" nach Englisch mit Beispielen - Kollokationen-Wörterbuch Englisch
- The incidence is between 1:30,000 and 1:100,000 and it is more often a sporadic mutation rather than an inherited condition.
- In about 50 percent of individuals with NF1, the disorder results from spontaneous (sporadic) mutations of the gene that occur for unknown reasons.
- Most cases of FOP occur as the result of a sporadic new mutation.
- It is believed to be due to a sporadic mutation, since parents of affected children usually have no evidence of the disease.
- In about half of all cases hypertrophic cardiomyopathy is familial, the remaining cases presumably arising from sporadic mutation.
- In individuals with the disorder, this sporadic genetic mutation is present in only some of the body's cells (mosaic pattern).
- In some individuals with NF2, the disorder is caused by new (sporadic) mutations of the gene that occur for unknown reasons.
- Autosomal recessive inheritance is the most likely, but sporadic mutations and autosomal dominant cases may also occur.
- It was later discovered, however, that the disorder is actually caused by a sporadic genetic mutation fitting an autosomal dominant genetic profile.
- There's generally a substantial overlap between these sporadic mutations and the ones that are mutated in the cancer's heritable form.
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