"mutation" nach Englisch mit Beispielen - Kollokationen-Wörterbuch Englisch
- In humans, simple deficiency of many serpins (e.g., through a null mutation) may result in disease (see Table 1).
- SOD2 knockout or null mutations cause growth inhibition on respiratory carbon sources in addition to decreased post-diauxic lifespan.
- This protein is considered a crucial component of the axon and presynaptic terminal, its null mutation leading to death within days after birth due to axon pathfinding defects.
- Initial studies demonstrated that most SI mutations result in lack of enzyme protein (i.e. null mutation) [ 26 ] .
- The recessive form of the disease is caused primarily by null mutations, although amino acid substitutions, splice junction mutations, and missense mutations have also been reported.
- Functional null mutations in this gene cause Carney complex (CNC), an autosomal dominant multiple neoplasia syndrome.
- Mice with null mutations ("knockouts") in Brn3a die at birth, due to developmental defects in the nucleus ambiguus, which is essential for respiration.
- Inner ear defects induced by null mutation of the isk gene.
- Clock mutant organisms can either possess a null mutation or an antimorphic allele at the Clock locus that codes for an antagonist to the wild-type protein.
- A null mutation in such a gene may be lethal to the embryo and such mutants would be missed in a basic screen.
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